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LABDATATM REFERENCE MANUAL

Quick Information on Test Results
Rapid Access, Easily Understood, Technical Information

Lab Data Cover

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This 160 page manual is a first in the profession to consolidate vital information in an easily readable quickly scanned format. Completely revised and updated, it includes SI Units, and "Look for" diagnostic hints for continued work-up, with "Values Out Of Normal Range."

SAMPLE CONTENTS:
These are excerpts from the book and do not contain total information.

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General Description of Multiple Tests, Including Blood Chemistries, Hematologies, Urinalysis, and Trace Minerals.

Phosphatase, Alkaline

Multiple Normals for Lab Variations

20-90 I.U./L
SI Units 383-1185 nanokats/L
SI conversion: conventional units X .01667 = nanokats/L
1.5-4 Bodansky Units (BU)
2.0-4.5 BU....and more

Alkaline Phosphatase is an enzyme that has optimum reaction in the laboratory in an alkaline pH (9-10) and is normally found in some concentration in human blood. Much of the body's alkaline phosphatase is produced by osteoblasts (bone cells)and therefore, any condition that stimulates increased osteoblastic activity, generally creates elevated blood levels of the enzyme.

Additional amounts of different forms of this enzyme are produced in the intestines, liver and placenta. In general, elevation... and more

Increased alkaline phosphatase may occur in the following conditions:

  • Metastatic bone cancer (destruction of bone [osteolytic] and attempts at repair [osteoblastic])
  • Bone development in children (production of new bone)
  • Bone fracture (production of new bone)
  • Osteogenic sarcoma (destruction of bone and attempts at repair)... and more

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What Drugs May Have Affected Your Patient's Results

Certain drugs may increase alkaline phosphatase including:

  • Adrenergic receptor blocking drugs (used to lower blood pressure-propranolol)
  • Anti-gout drugs (allopurinal, colchicine)
  • Anti-hypertensive agents (methyldopa)... and more

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What Foods May Have Altered The Test?

Decreases in alkaline phosphatase may occur as a result of ingestion of large amounts of oxalate-containing foods such as:
  Chocolate   Rhubarb   Cranberries   Chard   Spinach

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Values Out Of Normal Range. What Do You Do Next? Areas Not To Overlook.

VALUES OUT OF NORMAL RANGE, CONSIDER:
  • Signs of liver disease:
    Look for liver enlargement, especially with no evident jaundice
    Murphy's sign may be present (acute painful splinting on attempted deep inspiration. Palpation of right upper quadrant may cause same result)
    History of alcohol abuse
    Jaundice (skin, mucous membranes of mouth, sclerae)... and more
  • Signs of gallbladder diseases:
    Eructation (belching) nausea, with or without vomiting are common in chronic gallbladder disease. Nausea and vomiting are the rule when acute gallbladder disease is involved.
    Right upper quadrant pain and cramping are common after meals that contain spicy, fatty, greasy or fried foods... and more
  • Signs of bone involvement:
    Anemia (bone marrow depletion), pallor
    Generalized weakness
    Pain and aches over affected limbs... and more

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What Is Happening At The Cellular Level?

Trace mineral indications:
    Zinc/copper ratio greater than 10.0:1 in elevated alkaline phosphatase... and more
Prostate Specific Antigen (PSA)

2.7 ng.ml or less, males under 40
4.0 ng/ml or less, males over 40
SI Units 2.7 ng/ml or less, males under 40
....and more
Prostate-Specific Antigen (PSA) is normally found in the male prostate. It also is found in normal blood levels in benign, hypertrophied prostate glands, prostates that are cancerous with an intact capsule and those that are severely involved with wide-spread metastasis. The presence of the antigen is best considered as a monitor of treatment results. An elevated level correlated with a known prostatic cancer will commonly decrease with the advent of successful therapy targeted at the malignancy. It is NOT recommended as a general screening procedure for prostatic cancer.
    ...and more

Elevated Prostate-Specific Antigen (PSA) is found in:
  • Prostatic neoplasms (80% or more)
  • Some normal prostates or benign hypertrophy of the gland
  • Post-prostate massage, urinary catheterization, prostatic biopsy (allow 4 hours post-exam)
    ...and more
VALUES OUT OF NORMAL RANGE, CONSIDER:
PROSTATIC CANCER CLUES:
  • Patient over 50 years of age, most likely over 60 years; may be no early symptoms
  • Urinary retention/restriction of stream/hesitancy
  • Low back pain is common with metastasis; pelvis and lumbar spine are early sites. Pelvis and lumbar films may reveal metastatic lesions, but bone scan is more specific for early sites.
  • Prostate is rock hard, nodular and fixated
  • Prostate or rectal exam likely will not elevate PSA or acid phosphatase. The more manipulation of the gland that occurs, increases the chances that the lab results will be affected.
  • Urinary catheterization, prostate biopsy and prostate massage commonly falsely elevate test
  • Ultrasound testing may also affect blood levels ...and more

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Our doctors continue to applaud the "no-nonsense format." We know your practice will be enhanced quickly, with this addition to your library.

Lab Data Reference Manual       $59.95







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Dr and Mrs William Risley
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480-451-9746
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